Regulation of yeast mating-type interconversion: feedback control of HO gene expression by the mating-type locus.

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Regulation of yeast mating-type interconversion: feedback control of HO gene expression by the mating-type locus.

The ultimate product of yeast mating-type interconversion is a stable a/alpha diploid cell. A haploid cell carrying the HO gene gives rise to a diploid cell in a two-step process: first, the cell switches mating type as a result of genetic rearrangement (cassette substitution) catalyzed by HO; then, cells of opposite type mate to form a/alpha diploids. Mating-type interconversion does not occur...

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Healing of mat mutations and control of mating type interconversion by the mating type locus in Saccharomyces cerevisiae.

Homothallic yeasts switch cell types (mating types a and alpha) at high frequency by changing the alleles of the mating type locus, MATa and MATalpha. We have proposed in the cassette model that yeast cells contain silent MATa and MATalpha blocs ("cassettes"), copies of which can be substituted at the mating type locus for the resident information. The existence of silent cassettes was original...

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Interconversion of Yeast Mating Types

The HO gene promotes interconversion between a and a mating types. As a consequence, homothallic diploid cells are formed by mating between siblings descended from a single crH0 or a HO spore. In order to determine the frequency and pattern of the mating-type switch, we have used a simple technique by which the mating phenotype can be assayed without losing the cell to the mating process itself...

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Regulation of mating and meiosis in yeast by the mating-type region.

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 1983

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.80.10.3035